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1

F413C and A531V but not R894X myotonia congenita mutations cause defective endoplasmic reticulum export of the muscle-specific chloride channel CLC-1

Hinni Papponen, Marja Nissinen, Tuula Kaisto, Vilho V. Myllylä, Raili Myllylä, Kalervo Metsikkö

Journal:

Year:

2008

Language:

english

File:

PDF, 1.09 MB

english, 2008

2

Post-Translational Processing of Procollagens

KARI I. KIVIRIKKO, RAILI MYLLYLÄ

Journal:

Annals of the New York Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 906 KB

english, 1985

3

Prolyl 4-hydroxylase and its role in collagen synthesis

Pihlajaniemi, Taina, Myllylä, Raili, Kivirikko, Kari I.

Journal:

Journal of Hepatology

Year:

1991

Language:

english

File:

PDF, 355 KB

english, 1991

4

A compound heterozygote patient with Ehlers-Danlos syndrome type VI has a deletion in one allele and a splicing defect in the other allele of the lysyl hydroxylase gene

Birgitta Pousi, Timo Hautala, James C. Hyland, Jukka Schröter, Beate Eckes, Kari I. Kivirikko, Raili Myllylä

Journal:

Year:

1998

Language:

english

File:

PDF, 229 KB

english, 1998

5

A null-mutated lysyl hydroxylase gene in a compound heterozygote British patient with Ehlers-Danlos syndrome type VI

Jari Heikkinen, Birgitta Pousi, Michael Pope, Raili Myllylä

Journal:

Year:

1999

Language:

english

File:

PDF, 216 KB

english, 1999

6

Mutational analysis of the lysyl hydroxylase 1 gene (PLOD) in six unrelated patients with Ehlers-Danlos syndrome type VI: Prenatal exclusion of this disorder in one family

Heather N. Yeowell, Linda C. Walker, Brent Farmer, Jari Heikkinen, Raili Myllyla

Journal:

Year:

2000

Language:

english

File:

PDF, 141 KB

english, 2000

7

Lysyl hydroxylase 3 (LH3) modifies proteins in the extracellular space, a novel mechanism for matrix remodeling

Antti M. Salo, Chunguang Wang, Laura Sipilä, Raija Sormunen, Miia Vapola, Päivi Kervinen, Heli Ruotsalainen, Jari Heikkinen, Raili Myllylä

Journal:

Journal of Cellular Physiology

Year:

2006

Language:

english

File:

PDF, 383 KB

english, 2006

8

Expanding the lysyl hydroxylase toolbox: New insights into the localization and activities of lysyl hydroxylase 3 (LH3)

Raili Myllylä, Chunguang Wang, Jari Heikkinen, Andre Juffer, Outi Lampela, Maija Risteli, Heli Ruotsalainen, Antti Salo, Laura Sipilä

Journal:

Journal of Cellular Physiology

Year:

2007

Language:

english

File:

PDF, 346 KB

english, 2007

9

Lysyl hydroxylase 3 is secreted from cells by two pathways

Dr. Chunguang Wang, Marja-Maija Ristiluoma, Antti M. Salo, Sinikka Eskelinen, Raili Myllylä

Journal:

Journal of Cellular Physiology

Year:

2012

Language:

english

File:

PDF, 264 KB

english, 2012

10

Adenoviral Gene Transfer Restores Lysyl Hydroxylase Activity in Type VI Ehlers-Danlos Syndrome

Rauma, Tanja, Kumpumaki, Sanna, Anderson, Richard, Davidson, Beverly L., Ruotsalainen, Heli, Myllyla, Raili, Hautala, Timo

Journal:

The Journal of Investigative Dermatology

Year:

2001

Language:

english

File:

PDF, 126 KB

english, 2001

11

Collagen metabolism of mouse skeletal muscle during the repair of exercise injuries

Raili Myllylä, Antero Salminen, Leena Peltonen, Timo E. S. Takala, Veikko Vihko

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1986

Language:

english

File:

PDF, 2.56 MB

english, 1986

12

Localization of the gene encoding a novel isoform of lysyl hydroxylase

Claude Szpirer, Josiane Szpirer, Michèle Rivière, Pascale Vanvooren, Minna Valtavaara, Raili Myllylä

Journal:

Mammalian Genome

Year:

1997

Language:

english

File:

PDF, 482 KB

english, 1997

13

Collagen Biosynthesis in Systemic Scleroderma: Regulation of Posttranslational Modifications and Synthesis of Procollagen in Cultured Fibroblasts.

Peltonen, Leena, Palotie, Aarno, Myllyla, Raili, Krieg, Thomas, Oikarinen, Aarne

Journal:

The Journal of Investigative Dermatology

Year:

1985

File:

PDF, 2.11 MB

1985

14

A homozygous stop codon in the lysyl hydroxylase gene in two siblings with Ehlers–Danlos syndrome type VI

Hyland, James, Ala-Kokko, Leena, Royce, Peter, Steinmann, Beat, Kivirikko, Kari I., Myllylä, Raili

Journal:

Nature Genetics

Year:

1992

File:

PDF, 459 KB

1992

15

The genes encoding mouse lysyl hydroxylase isoforms map to Chromosomes 4, 5, and 9

Laura Sipilä, Marek Szatanik, Hanna Vainionpää, Heli Ruotsalainen, Raili Myllylä, Jean-Louis Guénet

Journal:

Mammalian Genome

Year:

2000

Language:

english

File:

PDF, 218 KB

english, 2000

16

Studies on the lysyl hydroxylase reaction. I. Initial velocity kinetics and related aspects

Ulla Puistola, Taina M. Turpeenniemi-Hujanen, Raili Myllylä, Kari I. Kivirikko

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1980

Language:

english

File:

PDF, 641 KB

english, 1980

17

Studies on the lysyl hydroxylase reaction. II. Inhibition kinetics and the reaction mechanism

Ulla Puistola, Taina M. Turpeenniemi-Hujanen, Raili Myllylä, Kari I. Kivirikko

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1980

Language:

english

File:

PDF, 580 KB

english, 1980

18

Preparation of antibodies to chick-embryo galactosylhydroxylysyl glucosyltransferase and their use for an immunological characterization of the enzyme of collagen synthesis

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1981

Language:

english

File:

PDF, 529 KB

english, 1981

19

A Connective Tissue Disorder Caused by Mutations of the Lysyl Hydroxylase 3 Gene

Antti M. Salo, Helen Cox, Peter Farndon, Celia Moss, Helen Grindulis, Maija Risteli, Simon P. Robins, Raili Myllylä

Journal:

The American Journal of Human Genetics

Year:

2008

Language:

english

File:

PDF, 944 KB

english, 2008

20

The glycosyltransferase activities of lysyl hydroxylase 3 (LH3) in the extracellular space are important for cell growth and viability

Chunguang Wang, Vuokko Kovanen, Päivi Raudasoja, Sinikka Eskelinen, Helmut Pospiech, Raili Myllylä

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

21

Mechanism of the Prolyl Hydroxylase Reaction : 1. Role of Co-substrates

Leena Tuderman, Raili Myllyla, Kari I. Kivirikko

Journal:

Nutrition Reviews

Year:

1982

Language:

english

File:

PDF, 187 KB

english, 1982

22

Glucosylation of Galactosylhydroxylysyl Residues in Collagen in vitro by Collagen Glucosyltransferase : Inhibition by Triple-Helical Conformation of the Substrate

Raili MYLLYLÄ, Leila RISTELI, Kari I. KIVIRIKKO

Journal:

Year:

1975

Language:

english

File:

PDF, 486 KB

english, 1975

23

Assay of Collagen-Galactosyltransferase and Collagen-Glucosyltransferase Activities and Preliminary Characterization of Enzymic Reactions with Transferases from Chick-Embryo Cartilage

Raili MYLLYLÄ, Leila RISTELI, Kari I. KIVIRIKKO

Journal:

Year:

1975

Language:

english

File:

PDF, 779 KB

english, 1975

24

Collagen Glucosyltransferase : Partial Purification and Characterization of the Enzyme from Whole Chick Embryos and Chick-Embryo Cartilage

Raili MYLLYLÄ, Leila RISTELL, Kari I. KIVIRIKKO

Journal:

Year:

1976

Language:

english

File:

PDF, 804 KB

english, 1976

25

Affinity Chromatography of Collagen Glycosyltransferases on Collagen Linked to Agarose

Leila RISTELI, Raili MYLLYLÄ, Kari I. KIVIRIKKO

Journal:

Year:

1976

Language:

english

File:

PDF, 558 KB

english, 1976

26

Studies on the Mechanism of Collagen Glucosyltransferase Reaction

Journal:

Year:

1976

Language:

english

File:

PDF, 646 KB

english, 1976

27

Mechanism of the Prolyl Hydroxylase Reaction : 1. Role of Co-substrates

Leena TUDERMAN, Raili MYLLYLÄ, Kari I. KIVIRIKKO

Journal:

Year:

1977

Language:

english

File:

PDF, 743 KB

english, 1977

28

Mechanism of the Prolyl Hydroxylase Reaction : 2. Kinetic Analysis of the Reaction Sequence

Raili MYLLYLÄ, Leena TUDERMAN, Kari I. KIVIRIKKO

Journal:

Year:

1977

Language:

english

File:

PDF, 806 KB

english, 1977

29

Metal Activation of Galactosylhydroxylysyl Glucosyltransferase, an Intracellular Enzyme of Collagen Biosynthesis

Raili MYLLYLÄ, Henrik ANTTINEN, Kari I. KIVIRIKKO

Journal:

Year:

1979

Language:

english

File:

PDF, 862 KB

english, 1979

30

Protein Disulphide-Isomerase Activity in Various Cells Synthesizing Collagen

Raili MYLLYLÄ, Juha KOIVU, Taina PIHLAJANIEMI, Kari I. KIVIRIKKO

Journal:

Year:

1983

Language:

english

File:

PDF, 595 KB

english, 1983

31

Monoclonal antibodies to human prolyl 4-hydroxylase

Matti HÖYHTYÄ, Raili MYLLYLÄ, Jaana PIUVA, Kari I. KIVIRIKKO, Karl TRYGGVASON

Journal:

Year:

1984

Language:

english

File:

PDF, 657 KB

english, 1984

32

A Large Duplication in the Gene for Lysyl Hydroxylase Accounts for the Type VI Variant of Ehlers-Danlos Syndrome in Two Siblings

Timo Hautala, Jari Heikkinen, Kari I. Kivirikko, Raili Myllylä

Journal:

Year:

1993

File:

PDF, 515 KB

1993

33

Structure and Expression of the Human Lysyl Hydroxylase Gene (PLOD): Introns 9 and 16 Contain Alu Sequences at the Sites of Recombination in Ehlers-Danlos Syndrome Type VI Patients

Jari Heikkinen, Timo Hautala, Kari I. Kivirikko, Raili Myllylä

Journal:

Year:

1994

File:

PDF, 501 KB

1994

34

Isolation of collagen glucosyltransferase as a homogeneous protein from chick embryos

Raili Myllylä, Henrik Anttinen, Leila Risteli, Kari I. Kivirikko

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1977

Language:

english

File:

PDF, 559 KB

english, 1977

35

A time-dependent increase in galactosylhydroxylysyl glucosyltransferase activity in human blood

Journal:

Clinica Chimica Acta

Year:

1985

Language:

english

File:

PDF, 396 KB

english, 1985

36

Markers of collagen metabolism in sera of patients with various rheumatic diseases

Raili Myllylä, Radim Bešcvašr, Milan Adam, Kari I. Kivirikko

Journal:

Clinica Chimica Acta

Year:

1989

Language:

english

File:

PDF, 630 KB

english, 1989

37

The lysyl hydroxylase isoforms are widely expressed during mouse embryogenesis, but obtain tissue- and cell-specific patterns in the adult

Antti M. Salo, Laura Sipilä, Raija Sormunen, Heli Ruotsalainen, Seppo Vainio, Raili Myllylä

Journal:

Year:

2006

Language:

english

File:

PDF, 588 KB

english, 2006

38

Dimerization of human lysyl hydroxylase 3 (LH3) is mediated by the amino acids 541–547

Jari Heikkinen, Maija Risteli, Outi Lampela, Paula Alavesa, Marjo Karppinen, André H. Juffer, Raili Myllylä

Journal:

Year:

2011

Language:

english

File:

PDF, 548 KB

english, 2011

39

Complete genomic structure of mouse lysyl hydroxylase 2 and lysyl hydroxylase 3/collagen glucosyltransferase

Heli Ruotsalainen, Sari Vanhatupa, Marjo Tampio, Laura Sipilä, Minna Valtavaara, Raili Myllylä

Journal:

Year:

2001

Language:

english

File:

PDF, 1.80 MB

english, 2001

40

The third activity for lysyl hydroxylase 3: galactosylation of hydroxylysyl residues in collagens in vitro

Chunguang Wang, Hanne Luosujärvi, Jari Heikkinen, Maija Risteli, Lahja Uitto, Raili Myllylä

Journal:

Year:

2002

Language:

english

File:

PDF, 252 KB

english, 2002

41

Characterization of cDNAs for mouse lysyl hydroxylase 1, 2 and 3, their phylogenetic analysis and tissue-specific expression in the mouse

Heli Ruotsalainen, Laura Sipilä, Erja Kerkelä, Helmut Pospiech, Raili Myllylä

Journal:

Year:

1999

Language:

english

File:

PDF, 1.21 MB

english, 1999

42

A nonsense codon of exon 14 reduces lysyl hydroxylase mRNA and leads to aberrant RNA splicing in a patient with Ehlers–Danlos syndrome type VI

Birgitta Pousi, Jari Heikkinen, Jukka Schröter, Michael Pope, Raili Myllylä

Journal:

Mutation Research/Mutation Research Genomics

Year:

2000

Language:

english

File:

PDF, 195 KB

english, 2000

43

The role of ascorbate in the prolyl hydroxylase reaction

Raili Myllylä, Eeva-Riitta Kuutti-Savolainen, Kari I. Kivirikko

Journal:

Biochemical and Biophysical Research Communications

Year:

1978

Language:

english

File:

PDF, 483 KB

english, 1978

44

Involvement of superoxide in the prolyl and lysyl hydroxylase reactions

Raili Myllylä, Lutz M. Schubotz, Ulrich Weser, Kari I. Kivirikko

Journal:

Biochemical and Biophysical Research Communications

Year:

1979

Language:

english

File:

PDF, 297 KB

english, 1979

45

A rapid and sensitive assay for protein disulphide isomerase activity

Raili Myllylä, Jouko Oikarinen

Journal:

Journal of Biochemical and Biophysical Methods

Year:

1983

Language:

english

File:

PDF, 320 KB

english, 1983

46

Monoclonal Antibodies to Collagen Hydroxylases and Their Use for the Localization of the Genes for These Enzymes on Human Chromosomes

RAILI MYLLYLÄ, LEILA PAJUNEN, MATTI HÖYHTYÄ, TAINA TURPEENNIEMI-HUJANEN, KARL TRYGGVASON, KARI I. KIVIRIKKO

Journal:

Annals of the New York Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 120 KB

english, 1985

47

Characterization of cDNA and Genomic Clones for the α Subunit of Human Prolyl 4-Hydroxylase

TARJA HELAAKOSKI, KRISTIINA VUORI, TARJA PARKKONEN, RAILI MYLLYLÄ, LOUISE T. CHOW, KARI I. KIVIRIKKO, TAINA PIHLAJANIEMI

Journal:

Annals of the New York Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 171 KB

english, 1990

48

Molecular Biology of Prolyl 4-Hydroxylase

KARI I. KIVIRIKKO, TARJA HELAAKOSKI, KAISA TASANEN, KRISTIINA VUORI, RAILI MYLLYLÄ, TARJA PARKKONEN, TAINA PIHLAJANIEMI

Journal:

Annals of the New York Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 741 KB

english, 1990

49

Lack of Collagen Type Specificity for Lysyl Hydroxylase Isoforms

Wang, Chunguang, Valtavaara, Minna, Myllyla, Raili

Journal:

DNA and Cell Biology

Year:

2000

Language:

english

File:

PDF, 223 KB

english, 2000

50

Cloning of human lysyl hydroxylase: Complete cDNA-derived amino acid sequence and assignment of the gene (PLOD) to chromosome 1p36.3→p36.2

Hautala, Timo, Byers, Mary G., Eddy, Roger L., Shows, Thomas B., Kivirikko, Kari I., Myllyla, Raili

Journal:

Year:

1992

Language:

english

File:

PDF, 879 KB

english, 1992

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